Phosphodiesterase Inhibitors

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Phosphodiesterase Inhibitors

By Page, Clive

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Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958. In the decade of the '70s, various PDE isoenzymes were defined which led to the development of the second generation of PDE inhibitors. Currently a variety of these new inhibitors are under test as potential anti-inflammatory drugs. During the past five years, molecular biology has revealed a superfamily of these phosphodiesterase isoenzymes. This book summarizes the present state of knowledge, as well as giving a comprehensive description of the compounds available. It will be invaluable for everyone who wants to choose the most suitable PDE inhibitor for their research or who is dealing with such drugs in a clinical setting.

Key Features
* Utilizes actual testing and research of new PDE inhibitors
* Valuable for researchers and students alike

Subject: Allied Health & Medical -> Medical -> Pharmacology

Phosphodiesterase Inhibitors
Publisher: Elsevier S & T 08/1996
Imprint: Academic Press
Language: English
Length: 228 pages

ISBN 10: 0122107209
ISBN 13: 9780122107207
Print ISBN: 9780122107207

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