Principles of Computational Modelling in Neuroscience

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Principles of Computational Modelling in Neuroscience

By David Sterratt; Bruce Graham; Andrew Gillies; David Willshaw

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The nervous system is made up of a large number of interacting elements. To understand how such a complex system functions requires the construction and analysis of computational models at many different levels. This book provides a step-by-step account of how to model the neuron and neural circuitry to understand the nervous system at all levels, from ion channels to networks. Starting with a simple model of the neuron as an electrical circuit, gradually more details are added to include the effects of neuronal morphology, synapses, ion channels and intracellular signalling. The principle of abstraction is explained through chapters on simplifying models, and how simplified models can be used in networks. This theme is continued in a final chapter on modelling the development of the nervous system. Requiring an elementary background in neuroscience and some high school mathematics, this textbook is an ideal basis for a course on computational neuroscience.

Subject: Allied Health & Medical -> Medical -> Neuroscience

Principles of Computational Modelling in Neuroscience
1st edition
Publisher: Cambridge University Press 6/30/11
Imprint: Cambridge University Press
Language: English

ISBN 10: 1139036327
ISBN 13: 9781139036320
Print ISBN: 9780521877954

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