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1. Refer to the picture to the right to answer the following questions. a. Is the cell haploid or diploid? Explain your reasoning. b. How many chromosomes are in a haploid cell for this species? c. What stage of the cell cycle is the diagram representing? d. Circle one set of homologous chromosomes. e. Draw the cell as it would appear during metaphase of mitosis. Label the centromere, kinetochore and one pair of sister chromatids on one of the chromosomes in your drawing. f. How many chromosomes and DNA molecules would be present in a cell during: i. G1 of interphase? 1. # of chromosomes: _____________________________ 2. # DNA molecules: _______________________________ ii. anaphase of mitosis? 1. # of chromosomes: _____________________________ 2. # DNA molecules: _______________________________ 2 2. Dogs can have upright ears (E) or drooping ears (e). Another gene controls whether dogs bark (B) when following a scent or are silent (b). Upright ears and barking are due to dominant alleles located on different chromosomes. A dog with upright ears that barks is mated to another dog that also has upright ears but is silent. They have a litter of 10 puppies: 5 with upright ears that bark and 5 with drooping ears that bark. a. What are the most likely genotypes for each of the parent dogs? b. The upright ears, barking parent dog from part a is used in a testcross? i. What is the genotypes and phenotype of the testcross parent? ii. What are the genotypes, genotypic proportions, phenotypes and phenotypic proportions of the progeny from the cross? c. Two other traits in dogs are fur length and fur color. Long fur (L) is dominant to short fur (l) and golden fur (G) is dominant to white fur (g). A EeBBLlgg dog is crossed to a EeBbllGg dog. What are the probabilities for a puppy born from these parents to: i. Have the genotype EEBBllGg? _________________________________ ii. Have all dominant traits? _________________________________ iii. Have drooping ears, bark and have short, golden fur? ___________ iv. Have a male puppy that has long golden fur? _____________________ 3 3. You perform an experiment very similar to what Mendel did with his peas. You cross a true-breeding flat leaf plant with a true breeding curled leaf plant. The resulting F1 progeny all have curled leaves. The F1 progeny are then crossed to each other to get the F2 progeny. a. Which trait is dominant? b. Use the letter L to define your alleles. c. Write out the genotypes of each parent and the F1 progeny. i. True-breeding flat leaf plant: _____________________ ii. True-breeding curled leaf plant: ___________________ iii. F1 progeny: _____________________ d. What are the genotypes, genotypic frequencies, phenotypes and phenotypic frequencies of the F2 progeny? e. What is the probability that the F2 progeny will have 3 flat leaf progeny and 2 curled leaf progeny? f. What is the probability that there will be three curled leaf progeny? g. Another trait is leaf color, green leaves (G) are dominant to yellow leaves (g). If two individuals heterozygous for both gene are crossed, what is the probability they have a progeny that has the genotype Llgg or LLGg? 4 4. Pea plants can have purple flowers (F) or white flowers (f). The also can have tall stems (T) or dwarf stems (t). Suppose a tall, purple plant heterozygous for both traits is crossed with a tall plant (heterozygous for the T gene), and has white flowers. a. What are the genotypes of each of the plants? i. tall, purple flower plant: _____________________________ ii. tall, white flower plant: __________________________ b. What are the phenotypes and phenotypic ratios of the progeny (use the branching method)? c. If the flowers are crossed and have the following progeny: 67 tall with purple flowers, 63 tall with white flowers, 38 dwarf with purple flowers and 32 dwarf with white flowers. Perform a chi-square test to determine if these two genes follow Mendelian probabilities. State the degrees of freedom, the chi-square value and whether you accept or reject the hypothesis. i. How many of each phenotype are expected: 1. tall with purple flowers: ________________________________ 2. tall with white flowers: ________________________________ 3. dwarf with purple flowers: ________________________________ 4. dwarf with white flowers: ________________________________ ii. Calculated chi-square value: ______________________________________ iii. Degrees of freedom: ________________________________________________ iv. Do you accept or fail to accept the hypothesis?

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