This material may consist of step-by-step explanations on how to solve a problem or examples of proper writing, including the use of citations, references, bibliographies, and formatting. This material is made available for the sole purpose of studying and learning - misuse is strictly forbidden.Peroxisome proliferator activated receptor (PPAR) activators are considered as promising drugs for the treatment of T2DM. Thiazolidinediones (TZDs) are well known PPAR activators such as pioglitazone (Actos) and rosiglitazone (Avandia) . TZDs like pioglitazone induced PPAR activation lead to an increased PPAR-gamma mediated mRNA and protein levels involved in lipid and glucose metabolism by increasing insulin sensitivity. Pioglitazone ameliorates insulin resistance by utilizing circulating insulin in an...
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