Question

Using the equation for calculating dose from ingestion of groundwater, calculate the Hazard Quotient for drinking water containing allyl alcohol at a concentration of 50 µg/L. Use the following exposure assumptions: ingestion rate, 2 L/day; exposure frequency, 365 days/year; exposure duration; 10 years; body weight, 70 kg; averaging time, 3,650 days; safe human dose, 0.005 mg/kg-day (RfD from EPA). [Hints: (1) You will also need to use the HQ equation. (2) Pay attention to the units for each input and make any conversions necessary to make them work out!!] Show your work – meaning provide the equations filled in with the appropriate numbers along with your answer.

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Work-up
Given:
Concentration of allyl alcohol – 50 µg/L
Ingestion rate – 2L/day
Frequency – 365 days/year
Duration – 10 years
Body weight – 70 kg
Average Time – 3650 days
Safe Human Dose – 0.005 mg/kg-day
Formula:
Ingestion of Ground Water:
Dose (mg/kg.day) = (Chemical Concentration in water*Ingestion rate*Exposure frequency*Exposure duration) / Body weight*Averaging time...

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