Question

These are the questions that need to be answered for the paper "Oral, Capsulized, Frozen Fecal Microbiota Transplantation for Relapsing Clostridium difficile Infection"

1. What is the context of the paper-background
2. Summarize big picture aspect-impact
3. What is the central hypothesis to be tested
4. FOR each figure-what are the conclusions based upon?
5. What are the controls used in each figure?
6. What is WRONG with the data/interpretation?
7. What experiment would you do to check?
8. What are the major conclusions/results
9. What other experiments do the authors propose?

Solution Preview

This material may consist of step-by-step explanations on how to solve a problem or examples of proper writing, including the use of citations, references, bibliographies, and formatting. This material is made available for the sole purpose of studying and learning - misuse is strictly forbidden.

1. What is the context of the paper- background.

• Clostridium difficile is a bacterium that causes a debilitating and often deadly form of diarrhea especially in the elderly with other health complications. This microbe is a persistent problem due to the natural resistance it exhibits against many antibiotics commonly used against other microbes in addition several strains have recently acquired resistance to antimicrobials typically used against it (Vancomycin and Metronidazole).
• This combination of factors makes hospital acquired infections more likely.   When people are taking antibiotics for other infections they may subsequently acquire C. difficile and have an impoverished intestinal flora to mediate dominance of C. difficile in their gut.
• If it is true that normal flora weakened by antibiotic treatment does contribute to the virility of C. difficile then it is logical that replacement of the normal flora will help control the Clostridium infection.   
• Faecal transplantation, collecting faecal matter from uninfected family relative volunteers and placing the extracted bacterial flora from the donor sample into the digestive tract of a patient has shown promise as an effective treatment for intractable C. difficile infections. However the timing required for acquiring a fresh sample, testing it and preparing it for transplantation is prohibitive and may affect the quality of the sample.
• Another study showed that processed frozen samples from unrelated healthy donors implanted in the colon are effective in curing the infection but the delivery method is unnecessarily inconvenient.
• The current study presents data on the effectiveness of a new procedure where previously processed and frozen donor faecal material is placed into capsules and given orally to the patient....

This is only a preview of the solution. Please use the purchase button to see the entire solution

Related Homework Solutions

Biology Questions
Homework Solution
$125.00
Biology
Photosynthesis
Membrane
Chroloplast
Oxidative Phosphorylation
Mitochondria
Reactions
Energy
Sunlight
ATP
ADP
Schemes
Reactions
Water
Carbon
Protons
Experiments
Cell Structures
Homework Solution
$15.00
Cell Membrane
Organelles
Nucleus
Ribosome
Smooth ER
Rough ER
Lysosome
Golgi Apparatus
Mitochondrion
Photosynthesis Questions
Homework Solution
$38.00
Biology
Photosynthesis
Chemical Energy
Sunlight
Equations
Sugar
Equations
Ambient Light
Glass
Bicarbonate Solution
Carbon Dioxide
Leafs
Petri Dish
Tables
Relationships
Photosynthetic Rate
Coleus Sketch
Starch Production
Biology Discussion Questions
Homework Solution
$30.00
Biology
Viruses
Receptors
Genetic Deficiencies
Receptors
Nervous System
Neurons
Cells
Graphical Information
Viral Resistance
Experiments
Mitosis Lab Questions
Homework Solution
$48.00
Biology
Mitosis
Cells
Division
Cytokinesis
Prophase
Telophase
Schemes
Sections
Cell Cycle
Cell Wall
Nucleolus
Spindle Fibers
Chromosomes
Drawings
Stages
Discussion
Experiments
Biology Questions: Basic Cell Structure
Homework Solution
$48.00
Biology
DNA
Prokaryotes
Eukaryotes
Power
Iodine Stain
Onion Tissue
Animal Cells
Plant Cells
Toothpick
Cytoplasm
Chloroplast
Cell Membrane
Cell Wall
Microscope
Cell Organelle
Bacteria
Obervations
Experiments
Laboratory
Analysis
Get help from a qualified tutor
Live Chats