Question

The given paper is "Dealing with the Evolutionary Downside of CRISPR Immunity: Bacteria and Beneficial Plasmids"

1. What is the context of the paper-background
2. Summarize big picture aspect-impact
3. What is the central hypothesis to be tested
4. FOR each figure-what are the conclusions based upon?
5. What are the controls used in each figure?
6. What is WRONG with the data/interpretation?
7. What experiment would you do to check?
8. What are the major conclusions/results
9. What other experiments do the authors propose?

Solution Preview

This material may consist of step-by-step explanations on how to solve a problem or examples of proper writing, including the use of citations, references, bibliographies, and formatting. This material is made available for the sole purpose of studying and learning - misuse is strictly forbidden.

1. What is the context of the paper-background?
One of the major methods through which bacteria become resistant to antibiotics is by exchanging genes with other bacteria. However this method of entry into the bacterium has been exploited by bacteria phage to enter and attack the bacteria. One class of genes used by bacteria to defend themselves use RNAi and are called Clustered, Regularly Interspaced Short Palindromic Repeats or CRISPR. Bacteria with functional CRISPR or similar systems are not able to accomplish conjugation – and those that have lost this mechanism are susceptible to attack. This paper reports a series of experiments designed to understand the potential costs to maintaining or excising the CRISPR gene.

2. Summarize big picture aspect-impact.
Understanding the weaknesses of antimicrobial resistant bacteria has become crucial in developing new forms of treatment. The conjugation system provides a novel and natural point of attack to treat bacterial infections.

3. What is the central hypothesis to be tested
Populations of bacteria can respond to phage attacks by spreading functional CRISPR-Cas genes through the population but can also respond to antibiotics by eliminating the CRISPR-Cas system in the population....

This is only a preview of the solution. Please use the purchase button to see the entire solution

Related Homework Solutions

Biology Questions: Basic Cell Structure
Homework Solution
$48.00
Biology
DNA
Prokaryotes
Eukaryotes
Power
Iodine Stain
Onion Tissue
Animal Cells
Plant Cells
Toothpick
Cytoplasm
Chloroplast
Cell Membrane
Cell Wall
Microscope
Cell Organelle
Bacteria
Obervations
Experiments
Laboratory
Analysis
Microbiology Lab Questions
Homework Solution
$16.00
SIM Test Media
Starch Hydrolysis
Urease Test
Citrate Test
Phenol Red Broth
Biology
Laboratory
Chemistry
Medicine
Pets in America
Homework Solution
$18.00
Biology
Americans
Dogs
Cats
Reptiles
Birds
Household
History
Lizard
Pet Lovers
Emotional Stealth
Families
Children
Tails
Companionship
Biology Discussion Questions
Homework Solution
$13.00
Biology
Microbiota
Transplatation
Clostridium Difficile Infection
Experiments
Bacteria
Treatments
Antibiotics
Patients
Control Groups
Chronic Conditions
Experiments
Stem Cells
Homework Solution
$85.00
Biology
Stem Cells
Blastocyst
Differentiation. Antigens
Key Transcription
IPS Cells
ES Cells
Pluripotency
Lgr5+ Cells
Homeostasis
Inntesine
Colonic Crypt
Wnt Signaling
Crypt Functions
Vitro Equivalent
Derived Cells
Evolution Questions
Homework Solution
$30.00
Biology
Evolution
Continent
Fossil
Period
Hominid
Conditions
Evidence
Get help from a qualified tutor
Live Chats