Answer the following questions:

1. What kind of substances are more easily eliminated from the body at a lower urine pH? Why?
2. How would you give to a child who has swallowed a whole bottle of aspirin tablets to increase the elimination of this drug in urine?
3. A person ingests by accident to a lipophilic toxic agent. Explain how this agent would be eliminated from the body
4. Where does lead accumulate? What metal ion does lead replace?
5. Explain what first pass effect means in Toxicology. What are the consequences of this effect?

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