Immunology Practice Questions
1. In regard to cytokines, which is not true?
a. Dendritic cells are not a source.
b. They interfere with viral activity.
c. They are glycoproteins.
d. Control helper T-cell responses.
e. Interferon- (gamma type) is an example of a cytokine.

2. CD4+ cells
a. are cytotoxic cells.
b. recognize MHC class II molecules.
c. stimulate endothelial cells.
d. have no interleukin receptors on their surface.
e. are not committed to helper activity.

18. Which of the following cells may be responsible for severe asphyxiation?
a. CD4 cells.
b. Mast cells.
c. Marcorphages.
d. Natural killer cells.
e. Glial cells.

19. An attenuated form of the AIDS virus has been used in recent research to stimulate the anti-tumor effect of
a. B-cells.
b. Microphage cells.
c. CD-4 cells.
d. CD-8 cells.
e. Neutrophil cells.

21. Which of the following is associated with short-lived (temporary) immunity?
a. Attenuated virus injection.
b. Natural acquired active immunity.
c. Antigen injection.
d. Antibody injection.
e. Booster-vaccination.

22. Which of the following is not associated with monoclonal antibodies?
a. B-cells.
b. Neutrophils.
c. Myeloma cells.
d. Hybridoma cells.
e. lymphocyte cells.

24. Antigenic shift, whereby pieces of the RNA genome from separate viruses infect some host cells, is associated with
a. the Polio virus.
b. herpes virus type1 and herpes type2.
c. Reo virus.
d. orthomyxoviruses (for example the Flu Virus).
e. the AIDS virus.

26. CD4 protein is not present on the surface of
a. macrophages.
b. B-cells.
c. cytotoxic T-cells.
d. Glial cells.
e. Duodenal and colon cells.

28. Capsomeres consist of
a. sugar molecules.
b. lipids acids.
c. nucleic acids.
d. amino acids.
e. host membrane fragments.

29. Viruses are
a. obligate intracellular parasites.
b. noninfectious agents.
c. anaerobic cells.
d. aerobic prokaryotic cells.
e. visible with a light microscope.

For questions 33-36 choose from the following choices
a. Transformation of normal cells.
b. Lytic infection.
c. Persistent infection.
d. Latent infection.
e. Hematopoiesis.

33. Death of the host cell.

34. Continuous production of virus with no cell death.

35. Oncogenic virus.

36. Symptoms reappear sporadically.

39. A humoral response refers to
a. activation of T cells by macrophages.
b. activation of granulocytes.
c. activation of mast cells.
d. activation of dendritic cells.
e. activation of virgin B cells by helper T cells..

41. Macrophage-antigen complex cells that have class 1 MHC recognition sites will activate
a. Memory B -cells.
b. Helper T -cells.
c. Neutrophils.
d. Monocytes.
e. Cytotoxic T -cells.

42. In accordance with the dual receptor mechanism, which is false?
a. Cytotoxic T-cells have receptors for MHC class I proteins.
b. Helper T-cells have receptors for MCH class II proteins.
c. Class I MHC proteins are found on nucleated body cell surfaces.
d. Suppressor T cells are aroused as a result of dual recognition.
e. T-cells have Antigenic recognition sites.

43. Which term is used for quantification of bacterial phage?
a. focus of infection.
b. zone of inhibition
c. colony formation.
d. plaque forming units.
e. Cytopathic effect.

14. There is no vaccine available (as of December 2013) to cause proliferation of B-cell lymphocytes against the
a. Polio virus.
b. Chicken pox virus.
c. Herpes simplex virus.
d. Rubella virus.
e. Influenza virus.

TRUE & FALSE
45. Pneumocystis carinni is associated with Herpes type 2 virus.
46. Most nucleated body cells have class I (1) proteins on their cell surface membranes.
47. Mesothelin protein is present on all NK cell membranes.
48. In bone marrow transplant leukemic patients, Graft versus Host Disease reaction is due donor lymphocytes.
49. Mage proteins can provoke a strong attack from cytotoxic T cells.
50. The cure for cystic fibrosis may depend on the Adenovirus being used as a vector.

HIV comes in many strains which change rapidly and thus overwhelm the antibody response.
46. Mature macrophage cells contain Birbeck granules.
47. Shingles is not common and occurs in children with immunodeficiency.
48. Certain animal viruses may bring about genetic change in which in turn is responsible for neoplastic tissue development.
49. DNA replication of most DNA viruses occurs in the nucleus of the host cell.
50. The cure for cystic fibrosis may depend on the Adinovirus being used vector.

Immunology Practice Questions 1. In regard to cytokines, which i...