Mutations and Diseases (Guided notes)
is a change in DNA
Sometimes, just a single
Sometimes whole chunks of DNA get altered.
This can alter the
of the gene and the trait.
Mutations can be
to an organism.
Causes can be exposure to
Some diseases that are
2. Types of Mutations
Point mutation: a single point in the sequence is
For instance a
Sickle cell disease
G is changed to an A.
Frameshift mutation- a point mutation that involves a
which results in a shift in the reading frame.
Explain what you observe happening in the Chromosomal Mutations:
3. What happens when your DNA changes?
This can cause a disease, which can then be passed to
Genetic diseases are
but, they can be
4. Alexandria's Story
What disease did Alex have?
Attacks of terrible pain are called a
Alex was being monitored for blood clots that cause
5. What causes sickle cell disease?
Hemoglobin is a protein that makes up
A single letter in the DNA is changed, causing the cells to
6. A change in DNA changes the
Describe or sketch what this causes blood cells to look like:
7. Sickled blood cells get stuck in the
This leads to
- where your body tissues aren't getting enough oxygen
8. What is it like to live with sickle cell disease? (WATCH THE VIDEO ON YOUTUBE:
Sickle Cell Anemia: A Patient's Journey
List a few of Alexandria's symptoms:
9. Sickle Cell Disease
The change in the shape means that the blood cells don't move through vessels easily.
More Symptoms Include:
10. Why don't Alex's parents have the disease?
A person can be a
for a gene but not have the disease.
If their partner is also a carrier, a child could inherit
of the mutated gene.
These solutions may offer step-by-step problem-solving explanations or good writing examples that include modern styles of formatting and construction
of bibliographies out of text citations and references. Students may use these solutions for personal skill-building and practice.
Unethical use is strictly forbidden.