Subject Biology Biotechnology


A. Use of other computational tool(s) (taught in class or not) that clearly demonstrates improvement of the functional annotation of the PH domain or protein or both - include in both results and discussion along with figure(s)

B. Model and characterize the PH domain from any 2 distant homologs and compare the biophysical properties - include in both results and discussion along with figure(s). Point out unique features of your assigned protein's PH domain compared to the homolog.

Solution Preview

This material may consist of step-by-step explanations on how to solve a problem or examples of proper writing, including the use of citations, references, bibliographies, and formatting. This material is made available for the sole purpose of studying and learning - misuse is strictly forbidden.

B. Distant homologue used for comparison to human Gab3 PH domain is a homologue from Dictyostelium discoideum, soil-living amoeba belonging to the phylum Amoebozoa. First, the sequence of interest (found previously by using BLAST to search within Dictyostelium discoideum for putative homologues to Q8www8 sequence of Gab3 from human. Serine/threonine kinase with the following sequence was found:
>XP_646888.1 protein serine/threonine kinase [Dictyostelium discoideum AX4]
CDD was used to predict...

This is only a preview of the solution. Please use the purchase button to see the entire solution

Assisting Tutor
Get College Homework Help.

Are you sure you don't want to upload any files?

Fast tutor response requires as much info as possible.

Upload a file
Continue without uploading

We couldn't find that subject.
Please select the best match from the list below.

We'll send you an email right away. If it's not in your inbox, check your spam folder.

  • 1
  • 2
  • 3
Live Chats