Describe ways in which marks can activate and repress transcription for both types of modification.
For all modifications, describe any known mechanisms of action.
These solutions may offer step-by-step problem-solving explanations or good writing examples that include modern styles of formatting and construction of bibliographies out of text citations and references. Students may use these solutions for personal skill-building and practice. Unethical use is strictly forbidden.Discuss the effects of histone modification and DNA modification on Transcription.
In the eukaryotic cells, DNA in the nuclei wraps in the region of the octamer of histone protein that is known as nucleosome, i.e. ‘beads on a string,' that forms the basic element of chromatin. The structure of chromatin can be altered by various post-translational modifications of histone proteins residing on the N-terminal tail residues. These modifications include:
Acetylation: The lysine residue neutralizes...
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