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a) Oxidation of nutrients like fats, sugars and proteins in our body leads to the production of electrons that passes through the electron transport chain (ETC) and generate energy in the form of ATP. In oxidative phosphorylation, the flow of electrons from NADH and FADH2 to oxygen results in the pumping of protons from the mitochondrial matrix to the inner membrane space. This gradient of H+ can produce ATP by flowing through ATP synthetase in the mitochondrial inner membrane. Dinitrophenol (DNP) is an uncoupler of oxidative phosphorylation with an ability to separate the flow of electrons, disrupts the proton pump gradient reducing ATP synthesis. Therefore, uncoupling the electron transport chain leads to decreased production of ATP....
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