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Activity: Construct a DNA Model Instructions 1. On the following page, rearrange the nucleotides into a strand of DNA. The base pair can go in any order as long as they compliment each other. (build your strand so that it goes vertically (up and down) on the page). 2. In order to match the pairs, one of the nucleotides must be arranged upside down. This is intended. The sides of the DNA double helix are arranged in an antiparallel fashion. Think of them like lanes on a highway going different directions. To rotate the square. use the blue dot that extends when the picture is highlighted and hold it to drag it. 3. After your nucleotides are arranged, use the key below (matching the shape) to figure the order of your base pairs. Record the letters (Example: AATCCGAG) for the left side of your DNA strand. Key Adenine Cytosine Thymine Guanine Phosphate St CG- Deoxyribose 4. What is the base pair rule? (what letters go together) - and - 5. After you have recorded the left side, double check that you have the correct matching base. Record the right side of your strand (make sure you follow the base pair rule!).

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