Which one of the following options best represents the backbone arrangement of two peptide bonds?
1)CÎ±-CÎ±-C-N-CÎ±-CÎ±-C
2)CÎ±-C-N-CÎ±-C-N
3)C-N-CÎ±-CÎ±-C-N
4)CÎ±-N-C-C-N-CÎ±
5)CÎ±-N-CÎ±-C-CÎ±-N-CÎ±-C

Which of the following pairs of bonds within a peptide backbone show free rotation around both bonds?
N-C and CÎ±-C
C=O and N-CÎ±
C=O and N-C
CÎ±-C and N-CÎ±
N-CÎ± and N-C

Imagine a protein that is 500 amino acid residues long. It contains 350 residues that have acidic side chains, 50 residues that have basic side chains and the remaining 100 residues have side chains that are either polar uncharged, non-polar aliphatic or aromatic. How many Î±-carbons does this protein have?

How many peptide â€˜linkagesâ€™ (or peptide â€˜groupsâ€™) does this protein have?

How many Î±-carboxylic acid groups does this protein have?

How many Î±-amino groups does this protein have?

Will the isoelectric point (IEP or pI) of this protein be:
Select one:
below 7
about 7
above 7
unable to determine this from the information given.

Will the pH of the tissue, cell or sub-cellular organelle in which this protein is normally found most likely be (select one):
Select one:
below 7
about 7
above 7
unable to determine this from the information given.

If this protein is placed in a buffer at pH 7, will the sign of the charge on the molecule be (select one):
positive
zero
negative
unable to determine this from the information given.

Which one of the following describes the overall three-dimensional folding of a polypeptide?
Select one:
tertiary structure
secondary structure
quaternary structure
primary structure

Which one of the following refers to stable 3-dimensional arrangements of amino acid residues with recognizable shapes and features that develop within relatively localized regions of a protein?
Select one:
quaternary structure
primary structure
tertiary structure
secondary structure

Which one of the following types of interaction or bond is mainly responsible for the stability of primary structure in proteins?
Select one:
hydrogen bonds
covalent bonds
the â€˜hydrophobic effectâ€™
disulphide bonds
peptide bonds

Which one of the following types of interaction or bond is mainly responsible for the stability of secondary structure in proteins?
Select one:
hydrogen bond
covalent bonds
the â€˜hydrophobic effectâ€™
disulphide bonds
peptide bonds

Which one of the following types of interaction or bond is mainly responsible for the stability of tertiary structure in proteins?
hydrogen bonds
covalent bonds
the â€˜hydrophobic effectâ€™
disulphide bonds
peptide bonds

In the Î±-helix, the hydrogen bonds (select one):
Select one:
occur mainly between electronegative atoms of the R groups
are perpendicular to the axis of the helix
occur mainly between electronegative atoms of the backbone
occur only near the amino and carboxyl termini of the helix
occur only between some of the amino acids of the heliix

Which one of the following arrangements correctly shows the position of intra-chain hydrogen bonding (depicted as |||) in an Î±-helix?
Select one:
-C=O ||| O=C-
-N-H ||| H-R-
-C=O ||| H-N-
-C=O ||| H-C-
-N-H ||| H-N-

In an Î±-helix, the R-groups of the amino acid residues (select one):
Select one:
alternate between the outside and the inside of the helix
cause only right-handed helices to form
stack within the interior of the helix
generate the hydrogen bonds that form the helix
are found on the outside of the helix spiral

Amino acid residues commonly found in ÃŸ-turns are (select one):
Select one:
alanine (Ala) and glycine (Gly)
two cysteine (Cys) residues
proline (Pro) and glycine (Gly)
hydrophobic residues
histidine (His) residues

Is the following type of secondary structure inherently stable (i.e. stable in their own right)? Select YES if inherently stable, or NO if not:
Î±-helix
Select one:
Yes
No

Is the following type of secondary structure inherently stable (i.e. stable in their own right)? Select YES if inherently stable, or NO if not
ÃŸ pleated sheet
Select one:
Yes
No

Select one option from the list below to correctly fill in the blank in the following statement
â€œA ________ protein exists in a conformation that shows biological functionâ€.
Select one:
catalytic
structural
tertiary
three-dimensional
native

Which one of the following statements concerning the process of protein folding is false?
Select one:
It may be defective in some human diseases
It may involve a gradually decreasing range of conformational species
It may involve initial formation of a highly compact state
It may involve the initial formation of local secondary structures
It may be an essentially random process.

Which one of the following options best represents the backbone arr...