Describe how Paul Boyer's rotational catalysis mechanism and John W...

  1. Home
  2. Homework Library
  3. Chemistry
  4. Biochemistry
  5. Describe how Paul Boyer's rotational catalysis mechanism and John W...


Describe how Paul Boyer's rotational catalysis mechanism and John Walker's description of the F1-ATPase structure provided a mechanistic underpinning for much of Peter Mitchell's chemiosmotic theory of ATP production.

Solution PreviewSolution Preview

These solutions may offer step-by-step problem-solving explanations or good writing examples that include modern styles of formatting and construction of bibliographies out of text citations and references. Students may use these solutions for personal skill-building and practice. Unethical use is strictly forbidden.

Chemiosmotic theory

In addition to what was called the orthodox view of the coupling of phosphorylation to electron/hydrogen transfer from the aspect of substrate-level phosphorylation, Peter Mitchell developed a novel chemiosmotic theory in the 1960s to explain the phosphorylation process taking place in a complex supramolecular system of mitochondrial ATPase (Mitchell 1961). Based on a research of multi-enzyme catalyzed processes (Mitchell 1958), Mitchell predicted that supramolecular organization dictates the phosphorylation and oxidation coupling which differed a lot from mechanisms accepted among the bioenergetics community of that period. The whole idea of the chemiosmotic gradient and supramolecular systems capable of using it for a high energy process without any high-energy intermediates was not in a line with the image of energy as chemical bonds (Allchin 2002). Imagining the complex supramolecular structure involved in the process, he assumed that the driving force for the process of ATP synthesis is the channeling of a certain component through the membrane. What he postulated...

By purchasing this solution you'll be able to access the following files:

for this solution

or FREE if you
register a new account!

PayPal, G Pay, ApplePay, Amazon Pay, and all major credit cards accepted.

Find A Tutor

View available Biochemistry Tutors

Get College Homework Help.

Are you sure you don't want to upload any files?

Fast tutor response requires as much info as possible.

Upload a file
Continue without uploading

We couldn't find that subject.
Please select the best match from the list below.

We'll send you an email right away. If it's not in your inbox, check your spam folder.

  • 1
  • 2
  • 3
Live Chats