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Problems GROUP 1 Problem 1 Show a forward synthesis for the following retrosynthesis problem. OO+O Problem 2 Draw mechanisms for the following reactions. Use curved arrows to show electron flow for each step, and draw out all reactants to effectively show all arrow pushing. Problem 3 O O 1. NaOEt EtOH OEt 2. HCl Show a retrosynthesis and forward synthesis for the following reaction. Using Clayden, Chapter 28 as a guide, break bonds stepwise (use the squiggly line in ChemDraw to indicate the bonds you’re breaking in each step). Draw a detailed retrosynthesis that combines no more than 2 steps in one arrow and traces back to the reagents shown. Then, use your retrosynthesis to show the forward synthesis of the compound. O OH NMe 2 O O OO O O 1

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