QuestionQuestion

Find the global alignment for the sequences given below using Dynamic Programming. Show the matrix of the alignment and backtracking path for full credit. Parameters of the alignment are: match score = 2, mismatch score is -1, and gap penalty is 3.
ATTACAGCGACTTAGCGACGCA
ATAACGAGACTAGCGACGGATC

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Global Alignment Problem
String a[]: ATTACAGCGACTTAGCGACGCA
String b[]: ATAACGAGACTAGCGACGGATC
The dynamic programming algorithm based on Needleman-Wunsch’s approach has produced the below cost matrix. The final cost is the last element (bottom right), namely 19.
The 1st row and 1st column below are the initial conditions, where the elements are computed using the formula F[0,j] = -3j & F[i,0]= -3i (3 is the gap penalty).
Each string has 22 characters, so the values there are in the [0, -66] range (the top-left element is 0).
The remaining elements were computed as follows:...

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