QuestionQuestion

Compare and contrast key features of benign and malignant neoplasms.

“Cancer is known as a clonal disease, yet not all cells in a tumor mass can generate a new carcinoma”. Discuss the evidence to support this statement.

(a) Compare and contrast carcinogenic and mutagenic compounds.
(b) Giving appropriate examples of the two different types of molecules discuss how they each play important roles in tumorigenesis.

‘The hallmark of cancer is reached when cells have attained different degrees of independence’. Discuss this sentence providing examples illustrating your answer.   

“The tumorigenesis route requires the involvement of both mutagens and carcinogens”. Discuss this sentence providing examples illustrating your answer.   

“p53 cannot directly be considered to be a tumor suppressor gene as it does not validate the two-hit theory”. Discuss this sentence providing examples illustrating your answer.   

“In only a very small proportion of cases, cancer is seen as a hereditary disease, but it is always referred to as a genetic disease”. Please discuss this statement, providing examples to support your argument.

Compare and contrast the differences between carcinogenic and mutagenic compounds. Giving appropriate examples of the two different molecules discuss how they both play important roles in tumorigenesis.

“Cancer is known as a clonal disease, yet not all cells in a tumour mass can generate a new carcinoma”. Discuss this statement providing examples of molecular markers that are essential to fulfil such properties.

“The hallmark of cancer is reached when cells have attained different degrees of independence”. Discuss this sentence providing examples illustrating your answer.

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