QuestionQuestion

Make a short presentation, not more than 15 power point slide and Word document. The topic is rational drug design - new drugs or new approaches to destroy bacteria or virus or the pathogen.

Explain the data and what is the innovative part on it, what is new and different.

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Introduction

Influenza virus is continually changing and every decade or so, a dangerous new strain appears and poses a threat to public health. This year, there has been an outbreak of a new strain of H1N1 flu, more commonly known as swine flu. The H1N1 designation refers to the two molecules that cover the surface of the virus: hemagglutinin and neuraminidase. Together, these two molecules control the infectivity of the virus. Hemagglutinin plays the starring role as the virus approaches a cell, binding to polysaccharide chains on the cell surface and then injecting the viral genome into the cell. Neuraminidase, on the other hand, plays its major role after the virus leaves an infected cell. It ensures that the virus doesn't get stuck on the cell surface by clipping off the ends of these polysaccharide chains.

Neuraminidase inhibitors are antiviral drugs for influenza virus. Neuraminidases are enzymes that hydrolyse sialic acid groups from glycoproteins and plays important role in influenza virus replication....
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